Development and applications of CRISPR-Cas9 for genome engineering
. 2014. Development and applications of CRISPR-Cas9 for genome engineering. Cell. 157(6):1262-78. Google Scholar PubMed
Posts
Crystal structure of Cas9 in complex with guide RNA and target DNA.
/0 Comments/in Publications /by syn-adminNishimasu H, F Ran A, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O. 2014. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell. 156(5):935-49. Google Scholar PubMed
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
/0 Comments/in Publications /by syn-adminF Ran A, Hsu PD, Lin C-Y, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y et al.. 2013. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 154(6):1380-9. Google Scholar PubMed
DNA targeting specificity of RNA-guided Cas9 nucleases.
/0 Comments/in Publications /by syn-adminHsu PD, Scott DA, Weinstein JA, F Ran A, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O et al.. 2013. DNA targeting specificity of RNA-guided Cas9 nucleases. Nat Biotechnol. 31(9):827-32. Google Scholar PubMed
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
/0 Comments/in Publications /by syn-adminBikard D, Jiang W, Samai P, Hochschild A, Zhang F, Marraffini LA. 2013. Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Res. 41(15):7429-37. Google Scholar PubMed
Multiplex genome engineering using CRISPR/Cas systems.
/0 Comments/in Publications /by syn-adminCong L, F Ran A, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA et al.. 2013. Multiplex genome engineering using CRISPR/Cas systems. Science. 339(6121):819-23. Google Scholar PubMed
