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Spirodihydantoin is a minor product of 5-hydroxyisourate in urate oxidation.

Yu H, Niles JC, Wishnok JS, Tannenbaum SR.  2004.  Spirodihydantoin is a minor product of 5-hydroxyisourate in urate oxidation. Org Lett. 6(19):3417-20. Google Scholar PubMed

Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue.

Niles JC, Wishnok JS, Tannenbaum SR.  2001.  Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue. Org Lett. 3(7):963-6. Google Scholar PubMed