Posts

Development and applications of CRISPR-Cas9 for genome engineering

Hsu PD, Lander ES, Zhang F.  2014.  Development and applications of CRISPR-Cas9 for genome engineering. Cell. 157(6):1262-78. Google Scholar PubMed

Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

Nissim L, Perli SD, Fridkin A, Perez-Pinera P, Lu TK.  2014.  Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Mol Cell. 54(4):698-710. Google Scholar PubMed

Analog synthetic biology.

Sarpeshkar R.  2014.  Analog synthetic biology. Philos Trans A Math Phys Eng Sci. 372(2012):20130110. Google Scholar  PubMed

Common genetic variants modulate pathogen-sensing responses in human dendritic cells.

Lee MN, Ye C, Villani A-C, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, F Ran A, Slowikowski K et al..  2014.  Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science. 343(6175):1246980. Google Scholar  PubMed

Genome-scale CRISPR-Cas9 knockout screening in human cells.

Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D, Ebert BL, Root DE, Doench JG et al.  2014.  Genome-scale CRISPR-Cas9 knockout screening in human cells. Science. 343(6166):84-7. Google Scholar PubMed

Multiplex genome engineering using CRISPR/Cas systems.

Cong L, F Ran A, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA et al..  2013.  Multiplex genome engineering using CRISPR/Cas systems. Science. 339(6121):819-23. Google Scholar PubMed

Dissecting neural function using targeted genome engineering technologies.

Hsu PD, Zhang F.  2012.  Dissecting neural function using targeted genome engineering technologies. ACS Chem Neurosci. 3(8):603-10. Google Scholar PubMed