Posts

Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.

Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB et al.  2011.  Precise manipulation of chromosomes in vivo enables genome-wide codon replacement. Science. 333(6040):348-53. Google Scholar PubMed

Analysis of DNA repeats in bacterial plasmids reveals the potential for recurrent instability events.

Oliveira PH, Prather KJones, Prazeres DMF, Monteiro GA.  2010.  Analysis of DNA repeats in bacterial plasmids reveals the potential for recurrent instability events. Appl Microbiol Biotechnol. 87(6):2157-67. Google Scholar PubMed

Structural instability of plasmid biopharmaceuticals: challenges and implications.

Oliveira PH, Prather KJones, Prazeres DMF, Monteiro GA.  2009.  Structural instability of plasmid biopharmaceuticals: challenges and implications. Trends Biotechnol. 27(9):503-11. Google Scholar PubMed