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Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

Nissim L, Perli SD, Fridkin A, Perez-Pinera P, Lu TK.  2014.  Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Mol Cell. 54(4):698-710. Google Scholar PubMed

High-resolution mapping of the spatial organization of a bacterial chromosome.

Le TBK, Imakaev MV, Mirny LA, Laub MT.  2013.  High-resolution mapping of the spatial organization of a bacterial chromosome. Science. 342(6159):731-4. Google Scholar PubMed

Optical control of mammalian endogenous transcription and epigenetic states.

Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F.  2013.  Optical control of mammalian endogenous transcription and epigenetic states. Nature. 500(7463):472-6. Google Scholar PubMed. Google Scholar PubMed

Retroactivity controls the temporal dynamics of gene transcription.

Jayanthi S, Nilgiriwala KSoli, Del Vecchio D.  2013.  Retroactivity controls the temporal dynamics of gene transcription. ACS Synth Biol. 2(8):431-41. Google Scholar PubMed

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.

Bikard D, Jiang W, Samai P, Hochschild A, Zhang F, Marraffini LA.  2013.  Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Res. 41(15):7429-37. Google Scholar PubMed

Towards a whole-cell modeling approach for synthetic biology.

Purcell O, Jain B, Karr JR, Covert MW, Lu TK.  2013.  Towards a whole-cell modeling approach for synthetic biology. Chaos. 23(2):025112. Google Scholar PubMed

Determinants of specificity in two-component signal transduction.

Podgornaia AI, Laub MT.  2013.  Determinants of specificity in two-component signal transduction. Curr Opin Microbiol. 16(2):156-62. Google Scholar PubMedsports74.ru

Regulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus.

Gora KG, Cantin A, Wohlever M, Joshi KK, Perchuk BS, Chien P, Laub MT.  2013.  Regulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus. Mol Microbiol. 87(6):1277-89. Google Scholar PubMed