Posts

Analog synthetic biology.

Sarpeshkar R.  2014.  Analog synthetic biology. Philos Trans A Math Phys Eng Sci. 372(2012):20130110. Google Scholar  PubMed

Crystal structure of Cas9 in complex with guide RNA and target DNA.

Nishimasu H, F Ran A, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O.  2014.  Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell. 156(5):935-49. Google Scholar PubMed

High-resolution mapping of the spatial organization of a bacterial chromosome.

Le TBK, Imakaev MV, Mirny LA, Laub MT.  2013.  High-resolution mapping of the spatial organization of a bacterial chromosome. Science. 342(6159):731-4. Google Scholar PubMed

DNA targeting specificity of RNA-guided Cas9 nucleases.

Hsu PD, Scott DA, Weinstein JA, F Ran A, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O et al..  2013.  DNA targeting specificity of RNA-guided Cas9 nucleases. Nat Biotechnol. 31(9):827-32. Google Scholar PubMed

Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA.

Jonas K, Liu J, Chien P, Laub MT.  2013.  Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA. Cell. 154(3):623-36. Google Scholar PubMedveroxybd.com

Multiplex genome engineering using CRISPR/Cas systems.

Cong L, F Ran A, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA et al..  2013.  Multiplex genome engineering using CRISPR/Cas systems. Science. 339(6121):819-23. Google Scholar PubMed

Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers.

Briggs AW, Rios X, Chari R, Yang L, Zhang F, Mali P, Church GM.  2012.  Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res. 40(15):e117. Google Scholar PubMed

Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains.

Cong L, Zhou R, Kuo Y-C, Cunniff M, Zhang F.  2012.  Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nat Commun. 3:968. Google Scholar PubMed