Posts

A bacterial toxin inhibits DNA replication elongation through a direct interaction with the β sliding clamp.

Aakre CD, Phung TN, Huang D, Laub MT.  2013.  A bacterial toxin inhibits DNA replication elongation through a direct interaction with the β sliding clamp. Mol Cell. 52(5):617-28. Google Scholar PubMed

High-resolution mapping of the spatial organization of a bacterial chromosome.

Le TBK, Imakaev MV, Mirny LA, Laub MT.  2013.  High-resolution mapping of the spatial organization of a bacterial chromosome. Science. 342(6159):731-4. Google Scholar PubMed

Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA.

Jonas K, Liu J, Chien P, Laub MT.  2013.  Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA. Cell. 154(3):623-36. Google Scholar PubMedveroxybd.com

Regulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus.

Gora KG, Cantin A, Wohlever M, Joshi KK, Perchuk BS, Chien P, Laub MT.  2013.  Regulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus. Mol Microbiol. 87(6):1277-89. Google Scholar PubMed

Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks.

Abel S, Chien P, Wassmann P, Schirmer T, Kaever V, Laub MT, Baker TA, Jenal U.  2011.  Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks. Mol Cell. 43(4):550-60. Google Scholar PubMed

Modularity of the bacterial cell cycle enables independent spatial and temporal control of DNA replication.

Jonas K, Y Chen E, Laub MT.  2011.  Modularity of the bacterial cell cycle enables independent spatial and temporal control of DNA replication. Curr Biol. 21(13):1092-101. Google Scholar PubMed

A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW.

Modell JW, Hopkins AC, Laub MT.  2011.  A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW. Genes Dev. 25(12):1328-43. Google Scholar PubMed

A dynamic complex of signaling proteins uses polar localization to regulate cell-fate asymmetry in Caulobacter crescentus.

Tsokos CG, Perchuk BS, Laub MT.  2011.  A dynamic complex of signaling proteins uses polar localization to regulate cell-fate asymmetry in Caulobacter crescentus. Dev Cell. 20(3):329-41. Google Scholar PubMed

Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium.

Y Chen E, Tropini C, Jonas K, Tsokos CG, Huang KC, Laub MT.  2011.  Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium. Proc Natl Acad Sci U S A. 108(3):1052-7. Google Scholar PubMed