Posts

Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection.

Carr PA, Wang HH, Sterling B, Isaacs FJ, Lajoie MJ, Xu G, Church GM, Jacobson JM.  2012.  Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection. Nucleic Acids Res. 40(17):e132. Google Scholar PubMed

Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.

Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB et al.  2011.  Precise manipulation of chromosomes in vivo enables genome-wide codon replacement. Science. 333(6040):348-53. Google Scholar PubMed

A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW.

Modell JW, Hopkins AC, Laub MT.  2011.  A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW. Genes Dev. 25(12):1328-43. Google Scholar PubMed

Evolving a robust signal transduction pathway from weak cross-talk.

Siryaporn A, Perchuk BS, Laub MT, Goulian M.  2010.  Evolving a robust signal transduction pathway from weak cross-talk. Mol Syst Biol. 6:452. Google Scholar PubMed

Engineering a direct and inducible protein-RNA interaction to regulate RNA biology.

Belmont BJ, Niles JC.  2010.  Engineering a direct and inducible protein-RNA interaction to regulate RNA biology. ACS Chem Biol. 5(9):851-61. Google Scholar PubMed

Engineering alternative butanol production platforms in heterologous bacteria.

Nielsen DR, Leonard E, Yoon S-H, Tseng H-C, Yuan C, Prather KLJones.  2009.  Engineering alternative butanol production platforms in heterologous bacteria. Metab Eng. 11(4-5):262-73. Google Scholar PubMed

Programming cells by multiplex genome engineering and accelerated evolution.

Wang HH, Isaacs FJ, Carr PA, Sun ZZ, Xu G, Forest CR, Church GM.  2009.  Programming cells by multiplex genome engineering and accelerated evolution. Nature. 460(7257):894-8. Google Scholar PubMed

Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy.

Lu TK, Collins JJ.  2009.  Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc Natl Acad Sci U S A. 106(12):4629-34. Google Scholar PubMed