Crystal structure of Cas9 in complex with guide RNA and target DNA.
. 2014. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell. 156(5):935-49. Google Scholar PubMed
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A bacterial toxin inhibits DNA replication elongation through a direct interaction with the β sliding clamp.
/0 Comments/in Publications /by syn-adminAakre CD, Phung TN, Huang D, Laub MT. 2013. A bacterial toxin inhibits DNA replication elongation through a direct interaction with the β sliding clamp. Mol Cell. 52(5):617-28. Google Scholar PubMed
High-resolution mapping of the spatial organization of a bacterial chromosome.
/0 Comments/in Publications /by syn-adminLe TBK, Imakaev MV, Mirny LA, Laub MT. 2013. High-resolution mapping of the spatial organization of a bacterial chromosome. Science. 342(6159):731-4. Google Scholar PubMed
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
/0 Comments/in Publications /by syn-adminBikard D, Jiang W, Samai P, Hochschild A, Zhang F, Marraffini LA. 2013. Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Res. 41(15):7429-37. Google Scholar PubMed
Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA.
/0 Comments/in Publications /by syn-adminJonas K, Liu J, Chien P, Laub MT. 2013. Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA. Cell. 154(3):623-36. Google Scholar PubMedveroxybd.com
Towards a whole-cell modeling approach for synthetic biology.
/0 Comments/in Publications /by syn-adminPurcell O, Jain B, Karr JR, Covert MW, Lu TK. 2013. Towards a whole-cell modeling approach for synthetic biology. Chaos. 23(2):025112. Google Scholar PubMed
Synthetic analog computation in living cells.
/0 Comments/in Publications /by syn-adminDaniel R, Rubens JR, Sarpeshkar R, Lu TK. 2013. Synthetic analog computation in living cells. Nature. 497(7451):619-23. Google Scholar PubMed
Determinants of specificity in two-component signal transduction.
/0 Comments/in Publications /by syn-adminPodgornaia AI, Laub MT. 2013. Determinants of specificity in two-component signal transduction. Curr Opin Microbiol. 16(2):156-62. Google Scholar PubMedsports74.ru
Regulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus.
/0 Comments/in Publications /by syn-adminGora KG, Cantin A, Wohlever M, Joshi KK, Perchuk BS, Chien P, Laub MT. 2013. Regulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus. Mol Microbiol. 87(6):1277-89. Google Scholar PubMed
RNA-guided editing of bacterial genomes using CRISPR-Cas systems.
/0 Comments/in Publications /by syn-adminJiang W, Bikard D, Cox D, Zhang F, Marraffini LA. 2013. RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat Biotechnol. 31(3):233-9. Google Scholar PubMed
