Crystal structure of Cas9 in complex with guide RNA and target DNA.
. 2014. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell. 156(5):935-49. Google Scholar PubMed
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Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling.
/0 Comments/in Publications /by syn-adminPodgornaia AI, Casino P, Marina A, Laub MT. 2013. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structure. 21(9):1636-47. Google Scholar PubMed
Helix bundle loops determine whether histidine kinases autophosphorylate in cis or in trans.
/0 Comments/in Publications /by syn-adminAshenberg O, Keating AE, Laub MT. 2013. Helix bundle loops determine whether histidine kinases autophosphorylate in cis or in trans. J Mol Biol. 425(7):1198-209. Google Scholar PubMed
The microbial opsin family of optogenetic tools.
/0 Comments/in Publications /by syn-adminZhang F, Vierock J, Yizhar O, Fenno LE, Tsunoda S, Kianianmomeni A, Prigge M, Berndt A, Cushman J, Polle J et al. 2011. The microbial opsin family of optogenetic tools. Cell. 147(7):1446-57. Google Scholar PubMed
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription.
/0 Comments/in Publications /by syn-adminZhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. 2011. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nat Biotechnol. 29(2):149-53. Google Scholar PubMed
Integrated bioprocessing for the pH-dependent production of 4-valerolactone from levulinate in Pseudomonas putida KT2440.
/0 Comments/in Publications /by syn-adminMartin CH, Wu D, Prather KLJones. 2010. Integrated bioprocessing for the pH-dependent production of 4-valerolactone from levulinate in Pseudomonas putida KT2440. Appl Environ Microbiol. 76(2):417-24. Google Scholar PubMed
Direct and adaptor-mediated substrate recognition by an essential AAA+ protease.
/0 Comments/in Publications /by syn-adminChien P, Perchuk BS, Laub MT, Sauer RT, Baker TA. 2007. Direct and adaptor-mediated substrate recognition by an essential AAA+ protease. Proc Natl Acad Sci U S A. 104(16):6590-5. Google Scholar PubMed
Short constrained peptides that inhibit HIV-1 entry.
/0 Comments/in Publications /by syn-adminSia SK, Carr PA, Cochran AG, Malashkevich VN, Kim PS. 2002. Short constrained peptides that inhibit HIV-1 entry. Proc Natl Acad Sci U S A. 99(23):14664-9. Google Scholar PubMed
Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket.
/0 Comments/in Publications /by syn-adminEckert DM, Malashkevich VN, Hong LH, Carr PA, Kim PS. 1999. Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket. Cell. 99(1):103-15. Google Scholar PubMed
Temperature dependence of intramolecular dynamics of the basic leucine zipper of GCN4: implications for the entropy of association with DNA.
/0 Comments/in Publications /by syn-adminBracken C, Carr PA, Cavanagh J, Palmer AG. 1999. Temperature dependence of intramolecular dynamics of the basic leucine zipper of GCN4: implications for the entropy of association with DNA. J Mol Biol. 285(5):2133-46. Google Scholar PubMed
