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Bioprospecting in the genomic age.
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers.
Crystal structure of Cas9 in complex with guide RNA and target DNA.
DNA targeting specificity of RNA-guided Cas9 nucleases.
Design of plasmid DNA constructs for vaccines.
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription.
Identification and characterization of IS1 transposition in plasmid amplification mutants of E. coli clones producing DNA vaccines.
Design and characterization of a three-terminal transcriptional device through polymerase per second.