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Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains.
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription.
Peroxynitrite-induced reactions of synthetic oligonucleotides containing 8-oxoguanine.
DNA targeting specificity of RNA-guided Cas9 nucleases.
Temperature dependence of intramolecular dynamics of the basic leucine zipper of GCN4: implications for the entropy of association with DNA.
Genome engineering.
Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA.