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DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite.

June 1, 1999/0 Comments/in Publications /by syn-admin

Burney S, Niles JC, Dedon PC, Tannenbaum SR. 1999. DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite. Chem Res Toxicol. 12(6):513-20. Google Scholar PubMed

Tags: Deoxyribonuclease (Pyrimidine Dimer), Deoxyribonucleosides, DNA Damage, DNA Glycosylases, DNA Repair, DNA-Formamidopyrimidine Glycosylase, Endodeoxyribonucleases, Guanine, N-Glycosyl Hydrolases, Nitrates, Nucleic Acid Conformation, Oligonucleotides, Oxidants, Substrate Specificity, Uracil-DNA Glycosidase

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/wp-content/uploads/2016/03/sbc@mit-banner-NRM-2.png 0 0 syn-admin /wp-content/uploads/2016/03/sbc@mit-banner-NRM-2.png syn-admin1999-06-01 21:03:072016-02-08 19:42:17DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite.

Mass spectrometric identification of 4-hydroxy-2,5-dioxo-imidazolidine-4-carboxylic acid during oxidation of 8-oxoguanosine by peroxynitrite and KHSO5/CoCl2.

Peroxynitrite reacts with 8-nitropurines to yield 8-oxopurines.

Peroxynitrite-induced reactions of synthetic oligonucleotides containing 8-oxoguanine.

Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue.

The chemistry of DNA damage from nitric oxide and peroxynitrite.

Direct and adaptor-mediated substrate recognition by an essential AAA+ protease.

Spatial tethering of kinases to their substrates relaxes evolutionary constraints on specificity.

High-resolution mapping of the spatial organization of a bacterial chromosome.