Posts

Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling.

Podgornaia AI, Casino P, Marina A, Laub MT.  2013.  Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling. Structure. 21(9):1636-47. Google Scholar PubMed

Determinants of specificity in two-component signal transduction.

Podgornaia AI, Laub MT.  2013.  Determinants of specificity in two-component signal transduction. Curr Opin Microbiol. 16(2):156-62. Google Scholar PubMedsports74.ru

Using analyses of amino Acid coevolution to understand protein structure and function.

Ashenberg O, Laub MT.  2013.  Using analyses of amino Acid coevolution to understand protein structure and function. Methods Enzymol. 523:191-212. Google Scholar PubMed

Adaptive mutations that prevent crosstalk enable the expansion of paralogous signaling protein families.

Capra EJ, Perchuk BS, Skerker JM, Laub MT.  2012.  Adaptive mutations that prevent crosstalk enable the expansion of paralogous signaling protein families. Cell. 150(1):222-32. Google Scholar PubMed

Load-induced modulation of signal transduction networks.

Jiang P, Ventura AC, Sontag ED, Merajver SD, Ninfa AJ, Del Vecchio D.  2011.  Load-induced modulation of signal transduction networks. Sci Signal. 4(194):ra67. Google Scholar PubMed

Long signaling cascades tend to attenuate retroactivity.

Ossareh HR, Ventura AC, Merajver SD, Del Vecchio D.  2011.  Long signaling cascades tend to attenuate retroactivity. Biophys J. 100(7):1617-26. Google Scholar PubMed

A dynamic complex of signaling proteins uses polar localization to regulate cell-fate asymmetry in Caulobacter crescentus.

Tsokos CG, Perchuk BS, Laub MT.  2011.  A dynamic complex of signaling proteins uses polar localization to regulate cell-fate asymmetry in Caulobacter crescentus. Dev Cell. 20(3):329-41. Google Scholar PubMed