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Development and applications of CRISPR-Cas9 for genome engineering

Hsu PD, Lander ES, Zhang F.  2014.  Development and applications of CRISPR-Cas9 for genome engineering. Cell. 157(6):1262-78. Google Scholar PubMed

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.

F Ran A, Hsu PD, Lin C-Y, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y et al..  2013.  Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 154(6):1380-9. Google Scholar PubMed

RNA-guided editing of bacterial genomes using CRISPR-Cas systems.

Jiang W, Bikard D, Cox D, Zhang F, Marraffini LA.  2013.  RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat Biotechnol. 31(3):233-9. Google Scholar PubMed

Multiplex genome engineering using CRISPR/Cas systems.

Cong L, F Ran A, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA et al..  2013.  Multiplex genome engineering using CRISPR/Cas systems. Science. 339(6121):819-23. Google Scholar PubMed

Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection.

Carr PA, Wang HH, Sterling B, Isaacs FJ, Lajoie MJ, Xu G, Church GM, Jacobson JM.  2012.  Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection. Nucleic Acids Res. 40(17):e132. Google Scholar PubMed

Dissecting neural function using targeted genome engineering technologies.

Hsu PD, Zhang F.  2012.  Dissecting neural function using targeted genome engineering technologies. ACS Chem Neurosci. 3(8):603-10. Google Scholar PubMed

Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.

Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB et al.  2011.  Precise manipulation of chromosomes in vivo enables genome-wide codon replacement. Science. 333(6040):348-53. Google Scholar PubMed

Analysis of DNA repeats in bacterial plasmids reveals the potential for recurrent instability events.

Oliveira PH, Prather KJones, Prazeres DMF, Monteiro GA.  2010.  Analysis of DNA repeats in bacterial plasmids reveals the potential for recurrent instability events. Appl Microbiol Biotechnol. 87(6):2157-67. Google Scholar PubMed