Posts

Dissecting neural function using targeted genome engineering technologies.

Hsu PD, Zhang F.  2012.  Dissecting neural function using targeted genome engineering technologies. ACS Chem Neurosci. 3(8):603-10. Google Scholar PubMed

Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains.

Cong L, Zhou R, Kuo Y-C, Cunniff M, Zhang F.  2012.  Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nat Commun. 3:968. Google Scholar PubMed

A transcription activator-like effector toolbox for genome engineering.

Sanjana NE, Cong L, Zhou Y, Cunniff MM, Feng G, Zhang F.  2012.  A transcription activator-like effector toolbox for genome engineering. Nat Protoc. 7(1):171-92. Google Scholar PubMed

Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.

Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB et al.  2011.  Precise manipulation of chromosomes in vivo enables genome-wide codon replacement. Science. 333(6040):348-53. Google Scholar PubMed

Genome engineering.

Carr PA, Church GM.  2009.  Genome engineering.  Nat Biotechnol. 27(12):1151-62. Google Scholar PubMed