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Using analyses of amino Acid coevolution to understand protein structure and function.

Ashenberg O, Laub MT.  2013.  Using analyses of amino Acid coevolution to understand protein structure and function. Methods Enzymol. 523:191-212. Google Scholar PubMed

Spatial tethering of kinases to their substrates relaxes evolutionary constraints on specificity.

Capra EJ, Perchuk BS, Ashenberg O, Seid CA, Snow HR, Skerker JM, Laub MT.  2012.  Spatial tethering of kinases to their substrates relaxes evolutionary constraints on specificity. Mol Microbiol. 86(6):1393-403. Google Scholar PubMed

Adaptive mutations that prevent crosstalk enable the expansion of paralogous signaling protein families.

Capra EJ, Perchuk BS, Skerker JM, Laub MT.  2012.  Adaptive mutations that prevent crosstalk enable the expansion of paralogous signaling protein families. Cell. 150(1):222-32. Google Scholar PubMed

Determinants of homodimerization specificity in histidine kinases.

Ashenberg O, Rozen-Gagnon K, Laub MT, Keating AE.  2011.  Determinants of homodimerization specificity in histidine kinases. J Mol Biol. 413(1):222-35. Google Scholar PubMed