Posts

Towards a whole-cell modeling approach for synthetic biology.

Purcell O, Jain B, Karr JR, Covert MW, Lu TK.  2013.  Towards a whole-cell modeling approach for synthetic biology. Chaos. 23(2):025112. Google Scholar PubMed

Load-induced modulation of signal transduction networks.

Jiang P, Ventura AC, Sontag ED, Merajver SD, Ninfa AJ, Del Vecchio D.  2011.  Load-induced modulation of signal transduction networks. Sci Signal. 4(194):ra67. Google Scholar PubMed

Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks.

Abel S, Chien P, Wassmann P, Schirmer T, Kaever V, Laub MT, Baker TA, Jenal U.  2011.  Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks. Mol Cell. 43(4):550-60. Google Scholar PubMed

Long signaling cascades tend to attenuate retroactivity.

Ossareh HR, Ventura AC, Merajver SD, Del Vecchio D.  2011.  Long signaling cascades tend to attenuate retroactivity. Biophys J. 100(7):1617-26. Google Scholar PubMed

Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium.

Y Chen E, Tropini C, Jonas K, Tsokos CG, Huang KC, Laub MT.  2011.  Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium. Proc Natl Acad Sci U S A. 108(3):1052-7. Google Scholar PubMed

Signaling properties of a covalent modification cycle are altered by a downstream target.

Ventura AC, Jiang P, Van Wassenhove L, Del Vecchio D, Merajver SD, Ninfa AJ.  2010.  Signaling properties of a covalent modification cycle are altered by a downstream target. Proc Natl Acad Sci U S A. 107(22):10032-7. Google Scholar PubMed

A method for determining the robustness of bio-molecular oscillator models.

Ghaemi R, Sun J, Iglesias PA, Del Vecchio D.  2009.  A method for determining the robustness of bio-molecular oscillator models. BMC Syst Biol. 3:95. Google Scholar PubMed