Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.

/0 Comments/in /by

F Ran A, Hsu PD, Lin C-Y, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y et al..  2013.  Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 154(6):1380-9. Google Scholar PubMed

You might also like
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers.
Emerging relationships between cytochemical properties and sensory modality transmission in primary sensory neurons.
Distribution of 5-hydroxytryptamine-immunoreactive boutons on immunohistochemically-identified Renshaw cells in cat and rat lumbar spinal cord.
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.
Cytochemical characteristics of cat spinal neurons activated during fictive locomotion.
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system.
Backbone dynamics of homologous fibronectin type III cell adhesion domains from fibronectin and tenascin.
Peptidergic input to immunohistochemically-identified Renshaw cells.