Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.

/0 Comments/in /by

F Ran A, Hsu PD, Lin C-Y, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y et al..  2013.  Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 154(6):1380-9. Google Scholar PubMed

You might also like
Effect of sciatic nerve transection or TTX application on enzyme activity in rat spinal cord.
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.
Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.
Analysis of parvalbumin and calbindin D28k-immunoreactive neurons in dorsal root ganglia of rat in relation to their cytochrome oxidase and carbonic anhydrase content.
Multiplex genome engineering using CRISPR/Cas systems.
Efficient universal computing architectures for decoding neural activity.
Inhibiting Plasmodium falciparum growth and heme detoxification pathway using heme-binding DNA aptamers.
Helix bundle loops determine whether histidine kinases autophosphorylate in cis or in trans.